Padcev and advanced urothelial cancer

Padcev received accelerated approval for the treatment of locally advanced or metastatic urothelial cancer announced on Dec. 18, 2019.It specifically targets the cell adhesion molecule Nectin-4, which is highly expressed in urothelial cancers. “Antibody-drug conjugates are strategic tools in the targeted treatment of cancer. These conjugates combine the ability of monoclonal antibodies to target specific […]

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Air pollution and breast cancer in women

INTRODUCTION Air pollution consists of chemicals resulting from many human activities and natural resources, which can cause gene mutations. It is long known that urban air is polluted by gaseous and some solid particles, and long or short term exposure to these pollutants leads to various disease and mortality. Many of these solid or gas […]

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